Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty

PHASE4CompletedINTERVENTIONAL
Enrollment

160

Participants

Timeline

Start Date

September 28, 2017

Primary Completion Date

December 3, 2020

Study Completion Date

February 19, 2021

Conditions
Joint DiseasePain, AcutePain, Chronic
Interventions
DRUG

Cymbalta

"Duloxetine (Cymbalta) is a serotonin and norepinephrine dual reuptake inhibitor (SNRI) that is an effective treatment for painful diabetic neuropathy. It is approved for major depressive disorder, generalized anxiety disorder, diabetic peripheral neuropathy, fibromyalgia, and chronic musculoskeletal pain"

OTHER

Placebo

Placebo to compare outcomes against Duloxetine

Trial Locations (1)

10021

Hospital for Special Surgery, New York

All Listed Sponsors
lead

Hospital for Special Surgery, New York

OTHER

NCT03271151 - Effect of Duloxetine on Opioid Use After Total Knee Arthroplasty | Biotech Hunter | Biotech Hunter