248
Participants
Start Date
October 21, 2017
Primary Completion Date
April 1, 2024
Study Completion Date
June 20, 2024
Computerized Ventilator Protocol
Computerized Decision Support System which recommends changes to ventilator settings to promote physiologic levels of patient effort of breathing.
Esophageal Manometry
Esophageal Manometry Catheter to measure effort of breathing an transpulmonary pressure
Respiratory Inductance Plethysmography (RIP)
RIP bands to measure thoraco-abdominal synchrony during spontaneous breathing trials
Diaphragm Ultrasound
Daily measurement of diaphragm thickness and diaphragm contractile activity
Maximal Inspiratory Pressure
Prior to Spontaneous breathing trials, measurement of airway and esophageal maximal inspiratory pressure during airway occlusion
Children's Hospital Los Angeles, Los Angeles
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Children's Hospital of Philadelphia
OTHER
Children's Hospital Los Angeles
OTHER