11,414
Participants
Start Date
February 1, 2018
Primary Completion Date
September 30, 2025
Study Completion Date
September 30, 2025
Allisartan Isoproxil
Allisartan Isoproxil 240mg daily will be used to lower BP to below 120 mm Hg systolic.
Amlodipine 5mg
Amlodipine 5mg daily will be added to Allisartan Isoproxil and afterwards increased to 10mg daily, if necessary to reach the blood pressure goal (below 120 mm Hg systolic).
Standard treatment by current guideline
No BP-lowering medications are used until BP becomes ≥ 140 mm Hg systolic and/or 90 mm Hg diastolic. Medications are determined by investigators in lines with recommendations by current Chinese guidelines to decrease BP to lower than 140 mm Hg systolic and to lower than 90 mm Hg diastolic.
RECRUITING
Guangdong General Hospital, Guangzhou
XueQing Yu
OTHER