A Study of CDX-3379 and Cetuximab and in Patients With Advanced Head and Neck Squamous Cell Carcinoma

PHASE2TerminatedINTERVENTIONAL
Enrollment

30

Participants

Timeline

Start Date

March 27, 2018

Primary Completion Date

September 16, 2020

Study Completion Date

December 16, 2020

Conditions
Advanced Head and Neck Squamous Cell Carcinoma
Interventions
DRUG

CDX-3379 and cetuximab

Dose: 12 mg/kg CDX-3379 once every 3 weeks in combination with 400 mg/m2 cetuximab on the first day followed by weekly doses of 250 mg/m2 cetuximab.

Trial Locations (10)

15232

UPMC Hillman Cancer Center, Pittsburgh

19104

University of Pennsylvania Hospital, Abramson Cancer Center, Philadelphia

29425

Medical University of South Carolina, Charleston

30322

Emory University Winship Cancer Institute, Atlanta

37232

Vanderbilt University Medical Center, Nashville

45267

University of Cincinnati, Cincinnati

60612

Rush University Medical center, Chicago

63110

Washington University School of Medicine, St Louis

85724

The University of Arizona Cancer Center, Tucson

06511

Yale Cancer Center, New Haven

Sponsors
All Listed Sponsors
lead

Celldex Therapeutics

INDUSTRY

NCT03254927 - A Study of CDX-3379 and Cetuximab and in Patients With Advanced Head and Neck Squamous Cell Carcinoma | Biotech Hunter | Biotech Hunter