Effect of Combined Morphine and Duloxetine on Chronic Pain

PHASE4CompletedINTERVENTIONAL
Enrollment

81

Participants

Timeline

Start Date

March 12, 2018

Primary Completion Date

April 5, 2022

Study Completion Date

April 5, 2022

Conditions
Chronic Low Back PainChronic Neck Pain
Interventions
DRUG

Morphine

Subjects will be randomized into one of the treatment groups and will follow the assigned medication schedule for 10 weeks. Quantitative Sensory Testing (QST) will be performed on the subjects to compare pain threshold, pain tolerance, and wind up.

DRUG

Duloxetine

Subjects will be randomized into one of the treatment groups and will follow the assigned medication schedule for 10 weeks. Quantitative Sensory Testing (QST) will be performed on the subjects to compare pain threshold, pain tolerance, and wind up.

DRUG

Placebo

Subjects will be randomized into one of the treatment groups and will follow the assigned medication schedule for 10 weeks. Quantitative Sensory Testing (QST) will be performed on the subjects to compare pain threshold, pain tolerance, and wind up.

Trial Locations (1)

02114

Karina de Sousa, Boston

All Listed Sponsors
lead

Massachusetts General Hospital

OTHER

NCT03249558 - Effect of Combined Morphine and Duloxetine on Chronic Pain | Biotech Hunter | Biotech Hunter