Dolutegravir in Pregnant HIV Mothers and Their Neonates

PHASE3CompletedINTERVENTIONAL
Enrollment

268

Participants

Timeline

Start Date

January 22, 2018

Primary Completion Date

October 20, 2020

Study Completion Date

September 5, 2023

Conditions
HIV-1-infectionPregnancy Related
Interventions
DRUG

Dolutegravir

Patients randomized to the study drug will be commenced on an antiretroviral regimen comprising DTG 50mg once daily in combination with 2 NRTIs

DRUG

Standard of Care (EFV + 2 NRTI backbone)

Patients randomized to receive standard of care will receive the currently used antiretroviral regimens in keeping with national policy.

Trial Locations (2)

Unknown

University of Cape Town, Cape Town

Infectious Diseases Institute, Kampala

All Listed Sponsors
collaborator

UNITAID

OTHER

collaborator

University of Cape Town

OTHER

collaborator

Liverpool School of Tropical Medicine

OTHER

collaborator

Infectious Diseases Institute, Uganda

OTHER

collaborator

Radboud University Medical Center

OTHER

lead

University of Liverpool

OTHER

NCT03249181 - Dolutegravir in Pregnant HIV Mothers and Their Neonates | Biotech Hunter | Biotech Hunter