TCR-engineered T Cells in Solid Tumors (ACTengine IMA201-101)

PHASE1CompletedINTERVENTIONAL
Enrollment

7

Participants

Timeline

Start Date

December 19, 2018

Primary Completion Date

April 20, 2023

Study Completion Date

September 18, 2023

Conditions
Solid TumorCancerRecurrent Solid TumorsRefractory Solid Tumors
Interventions
BIOLOGICAL

IMA201 Product

The cell dose will be based on viable CD3+CD8+ HLA-Dextramer+ cells per body surface area (BSA) as defined by the Mosteller formula.

DIAGNOSTIC_TEST

IMADetect®

IMADetect® is developed as a companion diagnostic to aid in selecting patients with relapsed and/or refractory solid cancers who might be eligible for enrollment in clinical trials with investigational IMA201 therapy. IMADetect® is intended for investigational use only.

Trial Locations (5)

15232

University of Pittsburgh Medical Center, Pittsburgh

20246

Universitätsklinikum Hamburg-Eppendorf, Hamburg

53127

Universitätsklinikum Bonn, Venusberg-Campus 1, Bonn

77030

University of Texas MD Anderson Cancer Center, Houston

01307

Universitätsklinikum Carl Gustav Carus, Fetscherstr. 74, Dresden

All Listed Sponsors
lead

Immatics US, Inc.

INDUSTRY

NCT03247309 - TCR-engineered T Cells in Solid Tumors (ACTengine IMA201-101) | Biotech Hunter | Biotech Hunter