NCT03246451View on ClinicalTrials.gov

The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D

NACompletedINTERVENTIONAL
Enrollment

15

Participants

Timeline

Start Date

July 1, 2017

Primary Completion Date

December 10, 2017

Study Completion Date

December 10, 2017

Conditions
Glucose Metabolism Disorders
Interventions
DRUG

Placebo Oral Tablet

2-4 tablets in 14 days

DRUG

Metformin

1000-2000 mg in 14 days

DRUG

Saline

9 mg/ml saline infusion during experimental days

DRUG

Exendin (9-39)

Infusion of GLP-1 receptor antagonist used as a tool during experimental days

Trial Locations (1)

2900

Center for Diabetes Research, Gentofte Municipality

All Listed Sponsors
collaborator

University of Copenhagen

OTHER

lead

University Hospital, Gentofte, Copenhagen

OTHER

NCT03246451 - The Role of GLP-1 Receptor Signalling in the Glucose-lowering Effect of Metformin in Patients With T2D | Biotech Hunter | Biotech Hunter