Characteristics of Obstructive Sleep Apnea Syndrome Related Hypertension and the Effect of Continuous Positive Airway Pressure Treatment on Blood Pressure

CompletedOBSERVATIONAL
Enrollment

78

Participants

Timeline

Start Date

April 3, 2018

Primary Completion Date

December 30, 2021

Study Completion Date

December 30, 2021

Conditions
Hypertension Secondary
Interventions
OTHER

continuous positive airway pressure

Continuous positive airway pressure (CPAP) prevents the airway collapse, avoids the occurrence of intermittent hypoxemia and arousal, is the preferred treatment for OSAS and has been widely used in clinical. The investigator would compare the effect of CPAP treatment on awake and sleep BP level at the first night and 2 weeks therapy among three groups. Moreover, whether or not the sympathetic-parasympathetic nerve balance and the renin-angiotensin-aldosterone system are different in three groups would also be evaluated.

Trial Locations (1)

223300

Department Of Respiratory Medicine,Huai'an First People's Hospital,Nanjing Medical University, Huai'an

All Listed Sponsors
collaborator

The First Affiliated Hospital with Nanjing Medical University

OTHER

lead

Huai'an No.1 People's Hospital

OTHER

NCT03246022 - Characteristics of Obstructive Sleep Apnea Syndrome Related Hypertension and the Effect of Continuous Positive Airway Pressure Treatment on Blood Pressure | Biotech Hunter | Biotech Hunter