The Impact of Heart Rate on Central Blood Pressure in Sick Sinus Syndrome Patients With a Permanent Cardiac Pacemaker

PHASE4CompletedINTERVENTIONAL
Enrollment

27

Participants

Timeline

Start Date

June 30, 2015

Primary Completion Date

September 30, 2016

Study Completion Date

September 30, 2016

Conditions
Aortic Blood Pressure
Interventions
DEVICE

AAI 40 bpm

Cardiac pacemaker of the subjects is set to AAI-mode 40 bpm in the first and second part of the study

DEVICE

AAI 60 bpm

Cardiac pacemaker of the subjects is set to AAI-mode 60 bpm in the first and second part of the study

DEVICE

AAI 90 bpm

Cardiac pacemaker of the subjects is set to AAI-mode 90 bpm in the first and second part of the study

DRUG

Atenolol Pill

50 or 100 mg of atenolol is administered to subjects in the second part of the study

DRUG

Nebivolol Pill

5 mg of nebivolol is administered to subjects in the second part of the study

DRUG

Ivabradine Pill

5 or 7,5 mg of ivabradine is administered to subjects in the second part of the study

All Listed Sponsors
lead

Tartu University Hospital

OTHER

NCT03245996 - The Impact of Heart Rate on Central Blood Pressure in Sick Sinus Syndrome Patients With a Permanent Cardiac Pacemaker | Biotech Hunter | Biotech Hunter