Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease

NACompletedINTERVENTIONAL
Enrollment

77

Participants

Timeline

Start Date

September 15, 2017

Primary Completion Date

December 13, 2019

Study Completion Date

December 13, 2019

Conditions
Sickle Cell Disease
Interventions
BIOLOGICAL

Blood sampling

Blood sampling will be performed to assess hematological and hemorheological parameters

OTHER

Maximum Voluntary Contraction (MVC) test force

Maximum Voluntary Contraction (MVC) test force will be performed before and after a localized muscle endurance test

OTHER

Localized muscle endurance test

Subject will perform 4 series of 20 submaximal dynamic contractions at 50% of the MVC interspaced with 1 min recovery.

OTHER

Self-paced six-minute walk test

Self-paced six-minute walk test will be conducted according to the guidelines of the American Thoracic Society

Trial Locations (1)

69003

Hôpital Edouard Herriot, Lyon

All Listed Sponsors
lead

Hospices Civils de Lyon

OTHER

NCT03243812 - Muscle Function and Its Biological and Physiological Determinants in Sickle Cell Disease | Biotech Hunter | Biotech Hunter