10
Participants
Start Date
January 12, 2018
Primary Completion Date
October 21, 2020
Study Completion Date
October 21, 2020
Congenital diaphragmatic hernia resuscitation with an intact umbilical cord
10 infants with left or right sided congenital diaphragmatic hernia will be intubated and ventilation initiated while still attached to the placental circulation through the umbilical cord. In addition, at the same time, a nasogastric tube will be placed in the stomach to drain entrained air and secretions. After 5 minutes of resuscitation with the umbilical cord intact, the umbilical cord will be cut, infants separated from the placenta and resuscitation performed per routine neonatal resuscitation protocols. Feasibility, the optimal approach and maternal and infant tolerance to the procedure will be assessed as part of the study.
Children's Hospital Colorado, Aurora
University of Colorado, Denver
OTHER