Resuscitation of Infants With Congenital Diaphragmatic Hernia With an Intact Umbilical Cord

NACompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

January 12, 2018

Primary Completion Date

October 21, 2020

Study Completion Date

October 21, 2020

Conditions
Congenital Diaphragmatic Hernia
Interventions
PROCEDURE

Congenital diaphragmatic hernia resuscitation with an intact umbilical cord

10 infants with left or right sided congenital diaphragmatic hernia will be intubated and ventilation initiated while still attached to the placental circulation through the umbilical cord. In addition, at the same time, a nasogastric tube will be placed in the stomach to drain entrained air and secretions. After 5 minutes of resuscitation with the umbilical cord intact, the umbilical cord will be cut, infants separated from the placenta and resuscitation performed per routine neonatal resuscitation protocols. Feasibility, the optimal approach and maternal and infant tolerance to the procedure will be assessed as part of the study.

Trial Locations (1)

80045

Children's Hospital Colorado, Aurora

All Listed Sponsors
lead

University of Colorado, Denver

OTHER

NCT03242044 - Resuscitation of Infants With Congenital Diaphragmatic Hernia With an Intact Umbilical Cord | Biotech Hunter | Biotech Hunter