Enhancing Corticospinal Activation for Improved Walking Function

NACompletedINTERVENTIONAL
Enrollment

25

Participants

Timeline

Start Date

March 1, 2017

Primary Completion Date

March 1, 2020

Study Completion Date

July 1, 2021

Conditions
Spinal Cord Injuries
Interventions
OTHER

Motor Skill Training

Motor skill training will consist of activities that will be performed while standing to promote upright control (the toe-tapping activity will be performed while seated). Participants will perform each of the 6 different activities for one minute each, until 4 cycles of the circuit have been completed (approximately 25 minutes total). Motor training activities will be performed at an intensity of 40-59% of heart rate reserve (HRR). Toe tapping will provide the opportunity for scheduled rest. During MT, all participants will wear a heart rate monitor to ensure that the optimal HR range is achieved. HRR will be calculated from resting and peak heart rate measures obtained during baseline testing via administration of a graded-exercise test.

DEVICE

Transcranial direct current stimulation (tDCS)

The tDCS electrode placement is based on procedures shown to improve gait and balance in a single session when used in combination with gait training activities. tDCS electrodes can simultaneously activate the bilateral leg motor areas when placed at the midline of the scalp slightly anterior to the vertex (anode) and at the inion (cathode), with a current intensity of 2mA. The tDCS device is lightweight, and can be worn in a backpack during the MT activities. As reported previously, participants in the MT-only group will receive sham tDCS to maintain analogous study procedures.

Trial Locations (1)

30309

Shepherd Center, Inc., Atlanta

All Listed Sponsors
collaborator

National Institute on Disability, Independent Living, and Rehabilitation Research

FED

lead

Shepherd Center, Atlanta GA

OTHER

NCT03237234 - Enhancing Corticospinal Activation for Improved Walking Function | Biotech Hunter | Biotech Hunter