Effect of NAC on the Hematopoietic Reconstitution After Haploidentical Hematopoietic Stem Cell Transplantation

PHASE2CompletedINTERVENTIONAL
Enrollment

35

Participants

Timeline

Start Date

August 1, 2017

Primary Completion Date

July 1, 2018

Study Completion Date

December 1, 2018

Conditions
Haploidentical Hematopoietic Stem Cell Transplantation
Interventions
DRUG

N-acetyl-L-cysteine

Acute leukemia patients with complete remission, whose bone marrow endothelial cells were less than 0.1% detected before haploidentical hematopoietic stem cell transplantation, receive N-acetyl-L-cysteine (NAC) (orally at dosages of 400mg 3 times per day). NAC treatment begins from 14 days pre-allotransplant to 2 months after-allotransplant continuously in the absence of disease progression or unacceptable toxicity.

Trial Locations (1)

Unknown

Peking University People's Hospital, Beijng

All Listed Sponsors
lead

Peking University People's Hospital

OTHER

NCT03236220 - Effect of NAC on the Hematopoietic Reconstitution After Haploidentical Hematopoietic Stem Cell Transplantation | Biotech Hunter | Biotech Hunter