Perioperative Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients

PHASE4CompletedINTERVENTIONAL
Enrollment

82

Participants

Timeline

Start Date

September 7, 2016

Primary Completion Date

November 6, 2017

Study Completion Date

November 6, 2017

Conditions
Urinary Tract InfectionAsymptomatic Bacteriuria
Interventions
DRUG

Fosfomycin disodium

Fosfomycin disodium 4 g intravenously dissolved in 100 mL of normal saline 0.9% three times in the perioperative period of renal transplant surgery.

DRUG

Trimethoprim / Sulfamethoxazole

Trimethoprim / Sulfamethoxazole (160/800 mg) orally every 24 hours during the study follow-up (7 weeks)

DRUG

Intravenous placebo

Normal saline 0.9% 100 mL intravenous administered three times in the perioperative period of the renal transplant, at the same times corresponding to disodium fosfomycin

Trial Locations (1)

14080

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran, Mexico City

All Listed Sponsors
collaborator

Laboratorios Senosiain, S.A. de C.V.

INDUSTRY

lead

Instituto Nacional de Ciencias Medicas y Nutricion Salvador Zubiran

OTHER

NCT03235947 - Perioperative Fosfomycin in the Prophylaxis of Urinary Tract Infection in Kidney Transplant Recipients | Biotech Hunter | Biotech Hunter