A Study to Compare Daratumumab, Bortezomib, and Dexamethasone (DVd) vs Bortezomib and Dexamethasone (Vd) in Chinese Participants With Relapsed or Refractory Multiple Myeloma

PHASE3CompletedINTERVENTIONAL
Enrollment

213

Participants

Timeline

Start Date

November 30, 2017

Primary Completion Date

October 7, 2019

Study Completion Date

February 27, 2024

Conditions
Multiple Myeloma
Interventions
DRUG

Daratumumab

Daratumumab will be administered on Day 1 of Cycles 4-9, and then q4w thereafter.

DRUG

Velcade

Velcade will be administered at a dose of 1.3 mg/m\^2 SC on Days 1, 4, 8 and 11 of each 21-day cycle.

DRUG

Dexamethasone

Dex will be administered orally at 20 mg on Days 1, 2, 4, 5, 8, 9, 11 and 12 of the first 8 Velcade treatment cycles.

Trial Locations (27)

10048

National Taiwan University Hospital, Taipei

11490

Tri-Service General Hospital, Taipei

100032

Peking Union Medical College Hospital, Beijing

100034

Peking University First Hospital, Beijing

100044

Peking University People s Hospital, Beijing

100083

Peking University Third Hospital, Beijing

130021

The First Hospital of Jilin University, Changchun

200003

Shanghai Changzheng Hospital, Shanghai

200025

Ruijin Hospital Shanghai Jiao Tong University, Shanghai

210008

Nanjing Drum Tower Hospital, Nanjing

210009

Zhongda Hospital Southeast University, Nanjing

210029

Jiangsu Province Hospital, Nanjing

215006

First Affiliated Hospital SooChow University, Suzhou

300040

Tianjin cancer hospital, Tianjin

300052

Tianjin Medical University General Hospital, Tianjin

300320

Institute of Hematology and Blood Diseases Hospital, Tianjin

310020

First Affiliated Hospital Medical School of Zhejiang University, Hangzhou

First affiliated Hospital of Zhejiang University, Hangzhou

350001

Fujian Meidical University Union Hospital, Fuzhou

400037

Xinqiao Hospital of the Third Military Medical University, Chongqing

430030

Tongji Hospital, Tongji Medical College of HUST, Wuhan

450008

Henan Cancer Hospital, Zhengzhou

510080

Guangdong Provincial People's Hospital, Guangzhou

The First Affiliated Hospital Sun Yat sen University, Guangzhou

510515

Nanfang Hospital, Guangzhou

610041

West China Hospital Si Chuan University, Chengdu

710038

Tangdu Hospital, Xi'an

All Listed Sponsors
lead

Janssen Research & Development, LLC

INDUSTRY

NCT03234972 - A Study to Compare Daratumumab, Bortezomib, and Dexamethasone (DVd) vs Bortezomib and Dexamethasone (Vd) in Chinese Participants With Relapsed or Refractory Multiple Myeloma | Biotech Hunter | Biotech Hunter