Apixaban Versus Warfarin in Patients With Left Ventricular (LV) Thrombus

PHASE3CompletedINTERVENTIONAL
Enrollment

40

Participants

Timeline

Start Date

January 1, 2018

Primary Completion Date

March 31, 2021

Study Completion Date

May 31, 2021

Conditions
Acute Myocardial InfarctionLeft Ventricular ThrombosisAnticoagulants and Bleeding Disorders
Interventions
DRUG

Apixaban Oral Tablet [Eliquis]

Apixaban 5 mg BID for 3 months. Apixaban 2.5-mg BID doses will be used in a subset of patients with two or more of the following criteria: an age of at least 80 years, a body weight of no more than 60 kg, or a serum creatinine level of 1.5 mg per deciliter (133 μmol per liter) or more. Patients with advanced renal failure (CrCl between 15 ml/min and 29 mi/min) will also receive 2.5 mg BID.

DRUG

Warfarin

Dose-adjusted warfarin to achieve a target international normalized ratio (INR) of 2.0 to 3.0 for 3 months

Trial Locations (1)

Unknown

Hadassah Medical Organization, Jerusalem

All Listed Sponsors
lead

Hadassah Medical Organization

OTHER

NCT03232398 - Apixaban Versus Warfarin in Patients With Left Ventricular (LV) Thrombus | Biotech Hunter | Biotech Hunter