3,000
Participants
Start Date
July 24, 2017
Primary Completion Date
December 20, 2019
Study Completion Date
December 31, 2025
VOC detection in breath and in skin headspace
VOC will be detected in breath with off-line and on-line testing and in skin headspace with off-line testing
Breath sampling
Breath sampling for VOCs detections will be carried out using nano-sensor based devices (electronic nose)
Upper endoscopy with biopsies
Upper endoscopy with proper biopsy work-up will be used for identification and stratification of gastric lesions as well as acquisition of biopsies for microbiota testing
Colonoscopy with biopsies
Colonoscopy with proper biopsy or polypectomy material work-up will be used for identification and stratification of colorectal lesions as well as acquisition of biopsies for microbiota testing
Whole blood/ Plasma / serum sampling
Whole blood/Plasma/serum sampling will be used to obtain information for group stratification
Faecal sampling
Facal samples will be obtained for faecal occult blood testing as well as microbiota analysis
Histological examination of surgical specimen
Routine histological exam for patients undergoing curative or palliative surgery. Indication for surgery are set based on underlying condition. Study does not interfere with decision making for surgical treatment
Headspace analysis for biological material
VOC analysis from headspace of surgical specimen, biopsy materials, blood/plasma, microbiota etc.
University of Latvia, Riga
Collaborators (1)
Technion, Israel Institute of Technology
OTHER
Riga East University Hospital
UNKNOWN
JLM Innovation GmbH
UNKNOWN
University of Latvia
OTHER