124
Participants
Start Date
August 8, 2017
Primary Completion Date
February 28, 2018
Study Completion Date
February 28, 2018
VX-659
Tablet for oral administration.
TEZ/IVA
TEZ/IVA fixed-dose combination tablet for oral administration.
IVA
Tablet for oral administration.
Placebo (matched to VX-659/TEZ/IVA)
Placebo matched to VX-659 and TEZ/IVA.
TEZ
Tablet for oral administration.
VX-561
Tablet for oral administration.
Placebo (matched to VX-659/TEZ/VX-561)
Placebo matched to VX-659, TEZ and VX-561.
Columbia University Medical Center, New York
Northwell Health, Long Island Jewish Medical Center, New Hyde Park
Albany Medical College, Albany
SUNY Upstate Medical University, Syracuse
Children's Hospital of Pittsburgh of University of Pittsburgh Medical Center, Pittsburgh
The Johns Hopkins Hospital/ Johns Hopkins Hospital, David Rubenstein Child Health Building, Baltimore
University of Miami/Miller School of Medicine, Miami
Vanderbilt University Medical Center, Nashville
University of Tennessee Medical Center-Adult Cystic Fibrosis Clinic, Knoxville
Children's Foundation Research Center / Le Bonheur Children's Hospital, Memphis
Indiana University Health, Indianapolis
University of Michigan Health System, Ann Arbor
Helen DeVos Children's Hospital CF Center, Grand Rapids
The University of Iowa Hospitals and Clinics, Iowa City
Sanford Research / USD, Sioux Falls
Advocate Children's Hospital - Park Ridge / North Suburban Pulmonary and Critical Care Consultants, Morton Grove
Children's Mercy Hospital, Kansas City
Respiratory Diseases of Children & Adolescents, Oklahoma City
University of Utah / Primary Children's Medical Center, Salt Lake City
Seattle Children's Hospital, Seattle
Providence Pediatric Pulmonary & Allergy/Immunology Clinic, Spokane
Yale New Haven Hospital, New Haven
Boston Children's Hospital, Boston
University of Massachusetts Memorial Medical Center, Worcester
Rutgers-Robert Wood Johnson Medical School/ Rutgers-Robert Wood Johnson Medical School, Clinical Research Center, New Brunswick
Cork University Hospital, Cork
St. Vincent's University Hosptial, Dublin
Galway University Hospitals, Galway
University Hospital Limerick, Limerick
Carmel Medical Center, Haifa
Ruth Children's Hospital Rambam Health Care Campus, Haifa
Hadassah Medical Organization, Jerusalem
The Chaim Sheba medical center, Ramat Gan
Schneider Children's Medical Center, Tikvah
Papworth Hospital NHS Foundation Trust, Papworth Everard, Cambridge
University Hospital Llandough in Cardiff, Cardiff
Royal Devon and Exeter NHS Foundation Trust, Royal Devon and Exeter Hospital, Devon
The Newcastle upon Tyne Hospitals NHS Foundation Trust, The Royal Victoria Infirmary, Fulham
Greater Glasgow and Clyde NHS Board, Glasgow Clinical Research Facility, Glasgow
Southampton University Hospitals NHS Foundation Trust, Hampshire
Regional Respiratory Centre Belfast City Hospital, London
Royal Brompton & Harefied NHS Foundation Trust, London
University Hospital of South Manchester NHS Trust, North West Lung Centre, Manchester
Liverpool Heart and Chest Hospital, Merseyside
Nottingham University Hospitals NHS Trust, Nottingham
Ruth Children's Hospital Rambam Health Care Campus, Nottingham
Birmingham Heartlands Hospital, Birmingham
Vertex Pharmaceuticals Incorporated
INDUSTRY