An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression

PHASE2CompletedINTERVENTIONAL
Enrollment

90

Participants

Timeline

Start Date

February 26, 2018

Primary Completion Date

April 28, 2024

Study Completion Date

April 28, 2024

Conditions
Depressive Disorder
Interventions
BEHAVIORAL

Interpersonal Psychotherapy for Depressed Adolescents

IPT-A is an evidence-based intervention that aims to decrease depressive symptoms by helping adolescents improve their relationships and interpersonal interactions. It addresses one or more of four interpersonal problem areas: grief, role disputes, role transitions, and interpersonal deficits. The primary treatment techniques in IPT-A include emotion identification/expression, linking interpersonal events to mood, communication analysis, communication skill building, decision analysis, role playing, and assignment of interpersonal experiments (i.e. homework). In clinical trials, depressed adolescents treated with IPT-A demonstrated fewer depressive symptoms and better psychosocial functioning post-treatment than adolescents in control conditions.

DRUG

Selective Serotonin Reuptake Inhibitor

Fluoxetine, escitalopram, citalopram, fluvoxamine, or sertraline

OTHER

Usual Care

Therapists will implement therapy procedures that they usually use and believe to be effective in clinical practice. Therapists will use whatever methods they usually use to make decisions regarding the frequency of therapy sessions and whether to refer the adolescent to start an SSRI

Trial Locations (1)

55414

University of Minnesota, Minneapolis

All Listed Sponsors
collaborator

National Institute of Mental Health (NIMH)

NIH

lead

University of Minnesota

OTHER

NCT03222570 - An Adaptive Algorithm-Based Approach to Treatment for Adolescent Depression | Biotech Hunter | Biotech Hunter