Antihypertensive Effect of Different Doses of Rostafuroxin in Comparison With Losartan

PHASE2CompletedINTERVENTIONAL
Enrollment

240

Participants

Timeline

Start Date

December 31, 2015

Primary Completion Date

February 8, 2018

Study Completion Date

February 8, 2018

Conditions
Hypertension
Interventions
DRUG

Rostafuroxin

This is a potent, selective and safe inhibitor of this altered mechanism and has been proved to be effective in reducing blood pressure levels in Adducin mutated rat strains and in chronic Ouabain infused rat model.

DRUG

Losartan

COZAAR (losartan potassium) is an angiotensin II receptor (type AT1) antagonist. Losartan potassium, a nonpeptide molecule, is chemically described as 2-butyl-4-chloro-1-\[p-(o-1H-tetrazol-5-ylphenyl)benzyl\]imidazole- 5-methanol monopotassium salt.

Trial Locations (1)

100

Cvie Therapeutics Limited, Taipei

Sponsors
All Listed Sponsors
lead

Windtree Therapeutics

INDUSTRY

NCT03217825 - Antihypertensive Effect of Different Doses of Rostafuroxin in Comparison With Losartan | Biotech Hunter | Biotech Hunter