Hybrid Closed Loop Insulin Delivery System in Hypoglycemia

NACompletedINTERVENTIONAL
Enrollment

10

Participants

Timeline

Start Date

August 1, 2017

Primary Completion Date

May 31, 2022

Study Completion Date

October 1, 2024

Conditions
Type1diabetesHypoglycemia UnawarenessNocturnal HypoglycemiaHypoglycemia NightHypoglycemia
Interventions
DEVICE

MiniMed 670G system

Eligible subjects with type 1 diabetes will initiate hybrid closed-loop insulin delivery based on interstitial glucose monitoring via the MiniMed 670G system according to Medtronic's labeling. This system combines subject-delivered pre-meal boluses with automatic interprandial insulin delivery that includes automated functions for both predictive and threshold suspension of insulin delivery intended to minimize exposure to glucose levels \< 70 mg/dl.

Trial Locations (3)

19104

Clinical and Translational Research Center, Hospital of University of Pennsylvania, Philadelphia

Rodebaugh Diabetes Center, University of Pennsylvania, Philadelphia

University of Pennsylvania - Institute for Diabetes, Obesity and Metabolism, Philadelphia

All Listed Sponsors
collaborator

National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)

NIH

lead

University of Pennsylvania

OTHER

NCT03215914 - Hybrid Closed Loop Insulin Delivery System in Hypoglycemia | Biotech Hunter | Biotech Hunter