A Study of Nivolumab and Ipilimumab Combined With Chemotherapy Compared to Chemotherapy Alone in First Line NSCLC

PHASE3CompletedINTERVENTIONAL
Enrollment

719

Participants

Timeline

Start Date

August 24, 2017

Primary Completion Date

August 16, 2019

Study Completion Date

October 18, 2024

Conditions
Non-Small Cell Lung Cancer
Interventions
BIOLOGICAL

Ipilimumab

Specified dose on specified day

BIOLOGICAL

Nivolumab

Specified dose on specified day

DRUG

Carboplatin

Specified dose on specified day

DRUG

Paclitaxel

Specified dose on specified day

DRUG

Pemetrexed

Specified dose on specified day

DRUG

Cisplatin

Specified dose on specified day

Trial Locations (116)

8

Local Institution - 0021, Dublin

2250

Local Institution - 0086, Gosford

3000

Local Institution - 0033, Leuven

3084

Local Institution - 0036, Heidelberg

3128

Local Institution - 0089, Box Hill

5000

Local Institution - 0030, Córdoba

5042

Local Institution - 0040, Bedford Park

5510

Local Institution - 0042, Lucca

5800

Local Institution - 0028, Río Cuarto

6060

Local Institution - 0002, Gilly

6150

Local Institution - 0078, Murdoch

8500

Local Institution - 0026, Viedma

8800

Local Institution - 0001, Roeselare

11501

Local Institution - 0098, Mineola

13790

Local Institution - 0058, Johnson City

14033

Local Institution - 0013, Caen

14165

Local Institution - 0073, Berlin

15006

Local Institution - 0054, A Coruña

15213

Local Institution - 0047, Pittsburgh

15224

Local Institution - 0093, Pittsburgh

17602

Local Institution - 0006, Lancaster

20132

Local Institution - 0041, Milan

22027

Local Institution - 0097, Saint-Brieuc

22927

Local Institution - 0072, Großhansdorf

23040

Local Institution - 0077, La Paz

28041

Local Institution - 0052, Madrid

29010

Local Institution - 0055, Málaga

29414

Local Institution - 0094, Charleston

30060

Local Institution - 0029, Marietta

32207

Local Institution - 0045, Jacksonville

34295

Local Institution - 0012, Montpellier

34376

Local Institution - 0017, Immenhausen

39120

Local Institution - 0074, Magdeburg

40503

Local Institution - 0004, Lexington

43210

Local Institution - 0095, Columbus

44093

Local Institution - 0035, Nantes

44280

Local Institution - 0061, Guadalajara

46026

Local Institution - 0056, Valencia

48202

Local Institution - 0105, Detroit

53705

Local Institution - 0099, Madison

58675

Local Institution - 0019, Hemer

59037

Local Institution - 0071, Lille

67214

Local Institution - 0091, Wichita

69373

Local Institution - 0009, Lyon Cedex08

69500

Local Institution - 0010, Bron

70376

Local Institution - 0018, Stuttgart

75970

Local Institution - 0011, Paris

80131

Local Institution - 0043, Napoli

80909

Memorial Health Systems, Colorado Springs

81925

Local Institution - 0015, München

82131

Local Institution - 0016, Gauting

84770

Southwest Regional Cancer Clinic, St. George

91900

Local Institution - 0075, Veracruz, Veracruz

100142

Local Institution - 0139, Beijing

102206

Local Institution - 0113, Beijing

115478

Local Institution - 0024, Moscow

130012

Local Institution - 0106, Changchun

197758

Local Institution - 0025, Saint Petersburg

200030

Local Institution - 0112, Shanghai

200542

Local Institution - 0032, Craiova

310016

Local Institution - 0110, Hangzhou

310022

Local Institution - 0111, Zhejiang

400015

Local Institution - 0031, Cluj-Napoca

410000

Local Institution - 0144, Changsha

450003

Local Institution - 0148, Zhengzhou

450052

Local Institution - 0120, Zhengzhou

570311

Local Institution - 0146, Haikou

710038

Local Institution - 0108, Xi'an

2210855

Local Institution - 0129, Yokohama

2360051

Local Institution - 0114, Yokohama

2418515

Local Institution - 0134, Yokohama

2520612

Local Institution - 0079, Viña del Mar

3620806

Local Institution - 0102, Kitaadachi-gun

3718511

Local Institution - 0118, Maebashi

3738550

Local Institution - 0128, Ota-shi

5838588

Local Institution - 0135, Habikino-shi

5898511

Local Institution - 0103, Ōsaka-sayama

6500047

Local Institution - 0104, Kobe

6708520

Local Institution - 0119, Himeji-shi

6738558

Local Institution - 0131, Akashi-shi

7008558

Local Institution - 0136, Okayama

7308518

Local Institution - 0138, Hiroshima

7348511

Local Institution - 0137, Hiroshima

7500921

Local Institution - 0059, Santiago

7550241

Local Institution - 0132, Ube-shi

8420383

Local Institution - 0084, Santiago

9208641

Local Institution - 0115, Kanazawa

9518566

Local Institution - 0116, Niigata

9601295

Local Institution - 0101, Fukushima

06062

Local Institution - 0044, Plainville

C1426ANZ

Local Institution - 0014, Ciudad Autónoma de Buenos Aires

S2000DSV

Local Institution - 0027, Rosario

59075-740

Local Institution - 0068, Natal

98700-000

Local Institution - 0063, Ijuí

91350-200

Local Institution - 0067, Porto Alegre

89010-340

Local Institution - 0069, Blumenau

14780-070

Local Institution - 0064, Barretos

15090-000

Local Institution - 0065, São José do Rio Preto

20231-050

Local Institution - 0066, Rio de Janeiro

01327-001

Local Institution - 0070, São Paulo

H1T 2M4

Local Institution - 0090, Montreal

H3T 1E2

Local Institution - 0083, Montreal

H4A 3J1

Local Institution - 0082, Montreal

G5L 5T1

Local Institution - 0080, Rimouski

V94 F858

Local Institution - 0020, Limerick

0608648

Local Institution - 0127, Sapporo

0283695

Local Institution - 0100, Shiwa-gun

545-8586

Local Institution - 0130, Osaka

85-796

Local Institution - 0087, Bydgoszcz

41-902

Local Institution - 0022, Bytom

80-952

Local Institution - 0085, Gdansk

020122

Local Institution - 0034, Bucharest

08035

Local Institution - 0053, Barcelona

GU2 7XX

Local Institution - 0050, Guildford

SE1 9RT

Local Institution - 0049, London

TA1 5DA

Local Institution - 0048, Tauton

Sponsors
All Listed Sponsors
lead

Bristol-Myers Squibb

INDUSTRY