Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness

NACompletedINTERVENTIONAL
Enrollment

22

Participants

Timeline

Start Date

July 15, 2018

Primary Completion Date

December 1, 2021

Study Completion Date

February 28, 2022

Conditions
SchizophreniaBipolar DisorderSchizo Affective Disorder
Interventions
DEVICE

TDCS

1 mA of anodal stimulation will be applied to the left dorsal lateral cortex (F3) concurrent with working memory focused cognitive training for 20 minutes

DEVICE

Sham Stimulation

Participants will receive 20 seconds of 1 mA anodal stimulation applied to the left dorsal lateral cortex (F3) concurrent with working memory focused cognitive training to mimic the effect of the active condition

BEHAVIORAL

Cognitive Remediation

Participants complete 60 minutes of computer-based cognitive training. All tasks are adaptable in terms of difficulty and require working memory skills. Sessions always begin with N-back and complex span tasks completed concurrent with tDCS or sham stimulation. Other tasks selected from Happy Neuron software and experimental working memory tasks are used throughout the protocol.

BEHAVIORAL

Bridging Group

Participants complete 45 minutes of activities and discussion to practice engaging cognitive skills through performance of everyday activities and to learn strategies to use cognitive abilities most effectively. Curriculum generated from Action-based Cognitive Remediation and Compensatory Cognitive Training intervention manuals.

Trial Locations (1)

55417

Minneapolis VA Health Care System, Minneapolis, MN, Minneapolis

All Listed Sponsors
lead

VA Office of Research and Development

FED

NCT03208036 - Restoration of Cognitive Function With TDCS and Training in Serious Mental Illness | Biotech Hunter | Biotech Hunter