Nilotinib in Parkinson's Disease

PHASE2CompletedINTERVENTIONAL
Enrollment

76

Participants

Timeline

Start Date

October 16, 2017

Primary Completion Date

August 26, 2019

Study Completion Date

September 28, 2019

Conditions
Parkinson Disease
Interventions
DRUG

Cohort 1:Nilotinib Oral Capsules (150mg or 300mg)

2 capsules taken once daily

DRUG

Cohort 2: Nilotinib Oral Capsules (dose to be determined from Cohort 1)

2 capsules taken once daily

DRUG

Placebo

2 capsules taken once daily

Trial Locations (24)

10003

Beth Israel Medical Center, New York

12208

Albany Medical College, Albany

19107

University of Pennsylvania, Philadelphia

21093

John Hopkins University, Baltimore

22903

University of Virginia, Charlottesville

27705

Duke University Medical Center, Durham

29425

Medical University of South Carolina, Charleston

32607

University of Florida, Gainesville

33620

University of South Florida, Tampa

44195

Cleveland Clinic, Cleveland

45219

University of Cincinnati, Cincinnati

48109

University of Michigan, Ann Arbor

48824

Michigan State University, East Lansing

53226

Medical College of Wisconsin, Milwaukee

60612

Rush University Medical Center, Chicago

77030

Baylor College of Medicine, Houston

80045

University of Colorado at Denver, Aurora

85013

Barrow Neurological Institute, Sun City

89106

Cleveland Clinic - Las Vegas, Las Vegas

95817

University of California Davis, Sacramento

97239

Oregon Health and Science University, Portland

99202

Inland Northwest Research, Spokane

35294-0017

University of Alabama at Birmingham, Birmingham

02114

Massachusetts General Hospital, Boston

All Listed Sponsors
collaborator

University of Rochester

OTHER

collaborator

University of Iowa

OTHER

collaborator

Michael J. Fox Foundation for Parkinson's Research

OTHER

lead

Northwestern University

OTHER

NCT03205488 - Nilotinib in Parkinson's Disease | Biotech Hunter | Biotech Hunter