The Effect of Pre-operative Electrical Stimulation on Peripheral Nerve Regeneration.

PHASE2/PHASE3CompletedINTERVENTIONAL
Enrollment

38

Participants

Timeline

Start Date

October 1, 2017

Primary Completion Date

October 13, 2023

Study Completion Date

October 13, 2023

Conditions
Peripheral Nerve InjuriesSensory DeficitDigital Nerve Lesion
Interventions
PROCEDURE

Electrical Stimulation

"The experimental treatment involves implantation of 2 sterilized fine-gauge Teflon coated wires percutaneously. The ends of the wire are stripped for conductivity. Electrical stimulation is given at a fixed continuous frequency of 20Hz. The stimulus intensity is the maximum tolerable limit. The wires are then taped to the skin with surgical wound tape at a location away from the wound for strain relief. To ensure sterility, care is taken to dress the sutured wound and hand, as well apply the splint.~The wires are removed either immediately at the conclusion of the pre-operative appointment and immediately after surgery or at the first surgical follow-up with dressing change, within one week of surgery."

PROCEDURE

Sham Stimulation

"The experimental treatment involves implantation of 2 sterilized fine-gauge Teflon coated wires percutaneously. The ends of the wire are stripped for conductivity. Electrical stimulation is begun until the patient senses the stimulation, then the stimulation is discontinued.The wires are then taped to the skin with surgical wound tape at a location away from the wound for strain relief. To ensure sterility, care is taken to dress the sutured wound and hand, as well apply the splint.~The wires are removed either immediately at the conclusion of the pre-operative appointment and immediately after surgery or at the first surgical follow-up with dressing change, within one week of surgery."

Trial Locations (2)

T5H 3V9

Royal Alexandra Hospital, Edmonton

T5R2E1

University of Alberta Hospital, Edmonton

All Listed Sponsors
lead

University of Alberta

OTHER

NCT03205124 - The Effect of Pre-operative Electrical Stimulation on Peripheral Nerve Regeneration. | Biotech Hunter | Biotech Hunter