NCT03204305 - Brain Imaging of Cannabinoid Receptors | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 14, 2017

Primary Completion Date

March 31, 2020

Study Completion Date

March 31, 2020

Conditions

Cannabis Use DisorderCannabis Dependence, Continuous

Interventions

DRUG

11C-OMAR

11C-OMAR is a PET radiotracer that binds to cannabinoid type 1 receptors (CB1R). It is an analog of the CB1R antagonist/inverse agonist rimonabant. 11C-OMAR was developed, synthesized and validated for inhuman use at the Johns Hopkins University PET center.

DRUG

Cannabis

Cannabis will be administered to cannabis users. Doses include 0 and 25 mg THC.

Trial Locations (1)

21224

Johns Hopkins Bayview Medical Center, Baltimore

All Listed Sponsors

collaborator

National Institute on Drug Abuse (NIDA)

NIH

lead

Johns Hopkins University

OTHER