110
Participants
Start Date
July 1, 2017
Primary Completion Date
April 30, 2018
Study Completion Date
May 30, 2018
Epidural morphine
2 mg of morphine (0.4 mg/ml morphine in 5 ml normal saline) is administered through the epidural catheter at the end of surgery.
Epidural placebo
5 ml normal saline is administered through the epidural catheter at the end of surgery.
Single femoral nerve block
Single femoral nerve block is performed with 20 ml 0.5% ropivacaine under the guidance of ultrasonography and nerve stimulator after surgery.
Intravenous morphine analgesia
Intravenous morphine analgesia is provided with a patient-controlled analgesia pump which is established with 100 ml of 0.5 mg/ml morphine, programmed to deliver a 2 ml bolus with a lockout interval of 8-10 min and a background infusion of 0.5 ml/h.
Peking University First Hospital, Beijing
Peking University First Hospital
OTHER