Lung Volume Recruitment Combined With Expiratory Muscle Strength Training in ALS

NACompletedINTERVENTIONAL
Enrollment

23

Participants

Timeline

Start Date

March 1, 2018

Primary Completion Date

December 1, 2021

Study Completion Date

December 30, 2022

Conditions
Amyotrophic Lateral Sclerosis
Interventions
PROCEDURE

Expiratory Muscle Strength Training (EMST)

EMST uses a training device that has a valve set to 50% of a patient's maximum expiratory pressure (MEP). The patient exhales forcefully until the valve releases. Patients perform 5 sets of 5 repetitions a day, 5 days a week.

PROCEDURE

EMST + Lung Volume Recruitment (LVR)

"EMST uses a training device that has a valve set to 50% of a patient's maximum expiratory pressure (MEP). The patient exhales forcefully until the valve releases. Patients perform 5 sets of 5 repetitions a day, 5 days a week.~LVR is a technique to increase cough function that is performed with a resuscitation bag fitted with a mouthpiece and a one-way valve. The bag is used to expand the lungs, after which the patient makes a voluntary cough. Half of the participants will perform the LVR technique in addition to the ESMT technique."

Trial Locations (2)

32611

University of Florida, Gainesville

55455

University of Minnesota, Minneapolis

All Listed Sponsors
lead

University of Minnesota

OTHER

NCT03202017 - Lung Volume Recruitment Combined With Expiratory Muscle Strength Training in ALS | Biotech Hunter | Biotech Hunter