Optimisation of Follicular Recruitment in IVM Cycles

PHASE3CompletedINTERVENTIONAL
Enrollment

145

Participants

Timeline

Start Date

November 1, 2017

Primary Completion Date

December 31, 2022

Study Completion Date

December 31, 2022

Conditions
Infertility, FemalePolycystic Ovary Syndrome
Interventions
PROCEDURE

blood sampling

comparison between corifollitropin alfa and follitropin beta in IVM cycles

PROCEDURE

transvaginal ultrasound scanning

comparison between corifollitropin alfa and follitropin beta in IVM cycles

PROCEDURE

oocyte retrieval for IVM

comparison between corifollitropin alfa and follitropin beta in IVM cycles

DRUG

Corifollitropin Alfa

Single injection of 100 micrograms of corifollitropin alfa

DRUG

Follitropin beta

Daily injection (three days) of follitropin beta

DRUG

oral contraceptive pill pretreatment (Marvelon)

Daily administration of the oral contraceptive pill (Marvelon) for 21 days. Administration of the combined oral contraceptive pill will start after a blood test that demonstrates basal E2 levels and a negative serum hCG level.

Trial Locations (1)

1090

UZ Brussel, Brussels

All Listed Sponsors
collaborator

Merck Sharp & Dohme LLC

INDUSTRY

lead

Universitair Ziekenhuis Brussel

OTHER

NCT03197077 - Optimisation of Follicular Recruitment in IVM Cycles | Biotech Hunter | Biotech Hunter