NCT03195946View on ClinicalTrials.gov

Effects of Repeated Doses of Lu AF35700 on Drug Metabolizing Enzymes

PHASE1CompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

June 16, 2017

Primary Completion Date

January 3, 2018

Study Completion Date

January 3, 2018

Conditions
Drug Reactions
Interventions
DRUG

Lu AF35700

tablets for oral use, 10 mg/day

DRUG

Midazolam

syrup for oral use, 4mg/day

DRUG

Cocktail of CYP450 substrates

Caffeine tablets for oral use, 200 mg/day. Omeprazole tablets for oral use, 40 mg/day. Dextromethorphan tablets for oral use, 30 mg/day. Midazolam IV solution for Intravenous use, 0.025 mg/kg/day

Trial Locations (1)

Unknown

Covance Clinical Research Unit Ltd, Leeds

All Listed Sponsors
lead

H. Lundbeck A/S

INDUSTRY

NCT03195946 - Effects of Repeated Doses of Lu AF35700 on Drug Metabolizing Enzymes | Biotech Hunter | Biotech Hunter