100
Participants
Start Date
March 1, 2017
Primary Completion Date
August 31, 2021
Study Completion Date
August 12, 2022
Oral Glucose Tolerance Test
The oral glucose tolerance test (OGTT) measures the body's ability to use a type of sugar, called glucose, that is the body's main source of energy. An OGTT can be used to diagnose prediabetes and diabetes.
Hyperglycemic Clamp
Test of beta-cell function and insulin secretion. Involves increasing and maintaining blood glucose concentration with IV variable infusion of dextrose.
Isoglycemic Intravenous Glucose Test
Test which exposes pancreas to blood glucose levels matched to the ones obtained at the OGTT.
Hyperinsulinemic Euglycemic Clamp and 2H20
Test is used to assess insulin effects on hepatic glucose production.
Yale University, New Haven
National Institute of Diabetes and Digestive and Kidney Diseases (NIDDK)
NIH
Yale University
OTHER