Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans

NACompletedINTERVENTIONAL
Enrollment

12

Participants

Timeline

Start Date

August 31, 2016

Primary Completion Date

January 12, 2017

Study Completion Date

January 12, 2017

Conditions
Healthy
Interventions
OTHER

Thearubigins

Single oral intake of 94.9 mg of therubigins (isolated from black tea) in a flavanol-free, fruit flavored, non-dairy drink

OTHER

Theaflavins

Single oral intake of 120 µmol of an equimolar mixture of theaflavins (isolated from black tea) in a flavanol-free, fruit flavored, non-dairy drink. The theaflavin mix includes theaflavin, theaflavin-3-gallate and theaflavin-3,3'-gallate

OTHER

Procyanidin Dimer B2 (DB2)

Single oral intake of 120 µmol of Procyanidin Dimer B2 (DB2) (isolated from Theobroma cacao) in a flavanol-free, fruit flavored, non-dairy drink.

OTHER

(-)-Epigallocatechin-3-O-gallate (EGCG)

Single oral intake of 120 µmol of (-)-Epigallocatechin-3-O-gallate (EGCG)(isolated from green tea) in a flavanol-free, fruit flavored, non-dairy drink.

OTHER

(-)-Epicatechin-3-O-gallate (ECG)

Single oral intake of 120 µmol of (-)-Epicatechin-3-O-gallate (ECG) (isolated from green tea) in a flavanol-free, fruit flavored, non-dairy drink.

OTHER

(-)-Epicatechin (EC)

Single oral intake of 120 µmol of (-)-Epicatechin (EC) (isolated from green tea) in a flavanol-free, fruit flavored, non-dairy drink.

OTHER

(-)-Epigallocatechin (EGC)

Single oral intake of 120 µmol of (-)-Epigallocatechin (EGC) (isolated from green tea) in a flavanol-free, fruit flavored, non-dairy drink.

OTHER

Control

Single oral intake of a flavanol-free, fruit flavored, non-dairy drink.

Trial Locations (1)

95616

UC Davis, Davis

All Listed Sponsors
collaborator

Mars, Inc.

INDUSTRY

lead

University of California, Davis

OTHER

NCT03194620 - Absorption, Metabolism and Excretion of Dietary Polyphenolic Bioactives in Humans | Biotech Hunter | Biotech Hunter