NCT03193788 - Pemetrexed Maintenance in Patients With Urothelial Carcinoma Who Completed First Line Platinum-based Chemotherapy | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

January 31, 2017

Primary Completion Date

December 31, 2019

Study Completion Date

June 30, 2020

Conditions

Bladder CancerUreter CancerTransitional Cell Carcinoma

Interventions

DRUG

pemetrexed

Pemetrexed 500 mg/m2mixed in normal saline 100 mL as a 10 minute IV infusion on day 1 of each 21 day cycle

DRUG

Folic Acid

folic acid 1000 μg daily orally from 7 days prior to treatment initiation until the end of treatment

DRUG

Vitamin B12 Injection

vitamin B12 1000 μg IM 7 days prior to treatment initiation and the end of treatment

DRUG

Dexamethasone

Dexamethasone 4 mg twice orally for 3 days beginning the day before treatment until the end of treatment to minimize cutaneous reactions

Trial Locations (21)

21565

RECRUITING

Gil Medical Center, Incheon

Unknown

RECRUITING

Hallym University Medical Center, Hallym University College of Medicine, Anyang

RECRUITING

Fatima Hospital, Daegu

RECRUITING

National Health Insurance Service Ilsan Hospital, Goyang

RECRUITING

Hallym University Dongtan Sacred Heart Hospital, Hwaseong-si

RECRUITING

Dong-A University Medical Center, Pusan

RECRUITING

Inje University Haeundae Paik Hospital, Pusan

RECRUITING

Pusan National University Hospital, Pusan National University School of Medicine, Pusan

RECRUITING

Inje University Sanggye Paik Hospital, Seoul

RECRUITING

Kangbuk Samsung Hospital, Sungkyunkwan University School of Medicine, Seoul

RECRUITING

Korea University Anam Hospital, Seoul

RECRUITING

Seoul National University Hospital, Cancer Research Institute, Seoul National University College of Medicine, Seoul

RECRUITING

Seoul St. Mary's Hospital, College of Medicine, The Catholic University of Korea, Seoul

RECRUITING

Yonsei Cancer Center, Seoul

RECRUITING

St. Vincent's Hospital, The Catholic University of Korea, Suwon

RECRUITING

Uijeongbu St Mary's hospital, Catholic university of Korea, Uijeongbu-si

RECRUITING

Pusan National University Yangsan Hospital, Yangsan

700-712

RECRUITING

Keimyeong University Dongsan Medical Center, Daegu

301-721

RECRUITING

Chungnam University Hospital, Daejeon

138-736

RECRUITING

Asan Medical Center, Seoul

156-755

RECRUITING

Chung Ang University Hospital, Seoul