Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cannabis Use and Cognitive Outcomes in Schizophrenia

NACompletedINTERVENTIONAL
Enrollment

24

Participants

Timeline

Start Date

June 1, 2017

Primary Completion Date

June 30, 2021

Study Completion Date

June 30, 2021

Conditions
Repetitive Transcranial Magnetic Stimulation (rTMS)SchizophreniaCannabis Use DisorderCognition
Interventions
DEVICE

Repetitive Transcranial Magnetic Stimulation (rTMS)

On Day 1, the resting motor threshold (RMT) will be determined according to previous published methods \[Cardenas-Morales et al. 2013\] and the rTMS will be delivered at an intensity of 90% of the participant's RMT. rTMS will be administered at 20 Hz (25 trains, 30 pulses per train, 30 second intertrain interval).

DEVICE

Sham Repetitive Transcranial Magnetic Stimulation (rTMS)

On Day 1, the resting motor threshold (RMT) will be determined according to previous published methods \[Cardenas-Morales et al. 2013\] and the Sham rTMS will be delivered at an intensity of 90% of the participant's RMT. rTMS will be administered at 20 Hz with the B65 placebo coil (25 trains, 30 pulses per train, 30 second intertrain interval).

BEHAVIORAL

Weekly Counselling Session

In order to support participants in their abstinence plan, individual weekly sessions of supportive counselling will be administered over the course of the study on 1 time per week over 4 weeks (28 days of abstinence).

Trial Locations (1)

M6J1H4

Centre for Addiction and Mental Health, Toronto

All Listed Sponsors
lead

Centre for Addiction and Mental Health

OTHER

NCT03189810 - Effects of Repetitive Transcranial Magnetic Stimulation (rTMS) on Cannabis Use and Cognitive Outcomes in Schizophrenia | Biotech Hunter | Biotech Hunter