Radiation Therapy With Protons or Photons in Treating Patients With Liver Cancer

PHASE3RecruitingINTERVENTIONAL
Enrollment

186

Participants

Timeline

Start Date

January 26, 2018

Primary Completion Date

June 30, 2027

Study Completion Date

June 30, 2027

Conditions
Recurrent Hepatocellular CarcinomaStage III Hepatocellular Carcinoma AJCC v7Unresectable Hepatocellular Carcinoma
Interventions
PROCEDURE

Biospecimen Collection

Undergo blood sample collection

PROCEDURE

Computed Tomography

Undergo CT scan

OTHER

Laboratory Biomarker Analysis

Correlative studies

PROCEDURE

Magnetic Resonance Imaging

Undergo MRI

OTHER

Quality-of-Life Assessment

Ancillary studies

RADIATION

Radiation Therapy

Undergo proton therapy

RADIATION

Radiation Therapy

Undergo photon therapy

Trial Locations (27)

10035

RECRUITING

New York Proton Center, New York

10065

ACTIVE_NOT_RECRUITING

Memorial Sloan Kettering Cancer Center, New York

10604

ACTIVE_NOT_RECRUITING

Memorial Sloan Kettering Westchester, Harrison

11553

ACTIVE_NOT_RECRUITING

Memorial Sloan Kettering Nassau, Uniondale

11725

ACTIVE_NOT_RECRUITING

Memorial Sloan Kettering Commack, Commack

21201

RECRUITING

Maryland Proton Treatment Center, Baltimore

RECRUITING

University of Maryland/Greenebaum Cancer Center, Baltimore

30308

RECRUITING

Emory Proton Therapy Center, Atlanta

RECRUITING

Emory University Hospital Midtown, Atlanta

30322

RECRUITING

Emory University Hospital/Winship Cancer Institute, Atlanta

30342

RECRUITING

Emory Saint Joseph's Hospital, Atlanta

43210

RECRUITING

Ohio State University Comprehensive Cancer Center, Columbus

44106

RECRUITING

Case Western Reserve University, Cleveland

45069

RECRUITING

University of Cincinnati Cancer Center-West Chester, West Chester

45219

RECRUITING

University of Cincinnati Cancer Center-UC Medical Center, Cincinnati

48073

RECRUITING

Corewell Health William Beaumont University Hospital, Royal Oak

48085

RECRUITING

Corewell Health Beaumont Troy Hospital, Troy

48124

RECRUITING

Corewell Health Dearborn Hospital, Dearborn

60555

ACTIVE_NOT_RECRUITING

Northwestern Medicine Cancer Center Warrenville, Warrenville

63110

RECRUITING

Washington University School of Medicine, St Louis

77030

RECRUITING

M D Anderson Cancer Center, Houston

98109

RECRUITING

Fred Hutchinson Cancer Center, Seattle

98195

RECRUITING

University of Washington Medical Center - Montlake, Seattle

02114

RECRUITING

Massachusetts General Hospital Cancer Center, Boston

07920

ACTIVE_NOT_RECRUITING

Memorial Sloan Kettering Basking Ridge, Basking Ridge

07748

ACTIVE_NOT_RECRUITING

Memorial Sloan Kettering Monmouth, Middletown

07645

ACTIVE_NOT_RECRUITING

Memorial Sloan Kettering Bergen, Montvale

Sponsors

Lead Sponsor

All Listed Sponsors
collaborator

National Cancer Institute (NCI)

NIH

lead

NRG Oncology

OTHER