NCT03177538 - Corifollitropin Alfa Combined With Menotropin Versus Follitropin and Lutropin Alfa in Expected Suboptimal Responders | Biotech Hunter

Enrollment

Participants

Timeline

Start Date

September 4, 2017

Primary Completion Date

November 2, 2018

Study Completion Date

September 10, 2019

Conditions

Infertility, Female

Interventions

DRUG

Corifollitropin alfa and menotropin

"Procedure: Ovarian stimulation is performed by the combination of a single Corifollitropin alfa 150 mcg injection on menstrual cycle day 2-3 and daily menotropin administration at the dose of 150 IU from stimulation day 1-7 and at the dose of 300 IU from day 8 to the end of stimulation (maximal dose adjustment to 450 IU).~Other interventions: conventional GnRH antagonist protocol and in vitro fertilization (IVF/ICSI) cycle"

DRUG

Follitropin alfa and lutropin alfa

"Procedure: Ovarian stimulation is performed with daily 300 IU of Follitropin alfa and lutropin alfa starting on menstrual cycle day 2-3. Maximal allowed dose adjustment is 450 IU daily.~Other interventions: conventional GnRH antagonist protocol and in vitro fertilization (IVF/ICSI) cycle."

Trial Locations (1)

199034

D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology, Saint Petersburg

All Listed Sponsors

lead

D.O. Ott Research Institute of Obstetrics, Gynecology, and Reproductology

OTHER