Postoperative Pain in Total Knee Arthroplasty: a Comparison Between General and Spinal Anesthesia

PHASE4UnknownINTERVENTIONAL
Enrollment

60

Participants

Timeline

Start Date

June 1, 2017

Primary Completion Date

June 1, 2018

Study Completion Date

June 1, 2018

Conditions
Total Knee Replacement Surgery
Interventions
DRUG

Spinal Block

Intrathecal 10 mg Heavy Marcaine, 200 mcg Morphine + High volume local anesthesia infiltration Bupivacaine 5mg/ml + adrenaline 5 mcg/ml 3mg/kg IBW diluted with 100cc Normal Saline

DRUG

General anesthetic

1-3 mg IV propofol 0.5 mg/kg IV Rocuronium + Fentanyl 2-3 mcg/kg + Morphine 0.1mg/kg IV Maintenance: Volatile anesthetic + High volume local anesthesia infiltration Bupivacaine 5mg/ml + adrenaline 5 mcg/ml 3mg/kg IBW diluted with 100cc Normal Saline

DEVICE

Total knee replacement

A total knee arthroplasty surgery, which is not the intervention of interest

Sponsors
All Listed Sponsors
lead

Meir Medical Center

OTHER

NCT03176758 - Postoperative Pain in Total Knee Arthroplasty: a Comparison Between General and Spinal Anesthesia | Biotech Hunter | Biotech Hunter