10
Participants
Start Date
April 1, 2017
Primary Completion Date
December 30, 2018
Study Completion Date
March 30, 2019
iNKT cells
The patients received different doses of in vitro-expanded autologous iNKT cells through intravenous infusion. The dosage was escalated from 3x10\^7 cells/m2 to 6x10\^7 cells/m2 to 9x10\^7 cells/m2. The maximum tolerated dose (MTD) was defined as the last dose level, and the dosage would be up to 1x10\^10 cells/m2 if no MTD was observed after a 3+3 design.
IL-2
IL-2 will be given at a dose of 25,000 IU/kg/day for 5-14 days.
Tegafur
Tegafur will be given at a dose of 40\~60 mg bis in die (BID) 2 weeks.
Beijing Youan Hospital,Capital Medical University, Beijing
Beijing YouAn Hospital
OTHER