Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers

PHASE2CompletedINTERVENTIONAL
Enrollment

133

Participants

Timeline

Start Date

July 13, 2017

Primary Completion Date

June 23, 2025

Study Completion Date

June 23, 2025

Conditions
MedulloblastomaEpendymomaPineal Region TumorsChoroid Plexus TumorsAtypical/Malignant Meningioma
Interventions
DRUG

Nivolumab

Individuals will receive nivolumab at standard dose of 240 mg IV every 2 weeks for cycles 1 through 2, then doses of 480 mg every 4 weeks for a total of 14 additional doses

Trial Locations (3)

20892

National Institutes of Health Clinical Center, Bethesda

60611

Northwestern University, Chicago

77030-4096

UT MD Anderson Cancer Center, Houston

All Listed Sponsors
lead

National Cancer Institute (NCI)

NIH

NCT03173950 - Immune Checkpoint Inhibitor Nivolumab in People With Recurrent Select Rare CNS Cancers | Biotech Hunter | Biotech Hunter