Chronic Inflammatory Disease, Lifestyle and Treatment Response

CompletedOBSERVATIONAL
Enrollment

233

Participants

Timeline

Start Date

September 21, 2017

Primary Completion Date

July 22, 2020

Study Completion Date

April 30, 2021

Conditions
Autoimmune DiseasesInflammatory Bowel DiseasesCrohn Disease (CD)Colitis, Ulcerative (UC)Arthritis, Rheumatoid (RA)SpondylarthropathiesArthritis, Psoriatic (PsA)PsoriasisHidradenitis Suppurativa (HS)Uveitis
Interventions
OTHER

Primary exposure variable

"1. Upper tertile (33.3% of the total sample) based on the ratio: fibre/meat intake is associated with better treatment outcome~2. Low intake of red and processed meat (defined as below the lower tertile \[33.3% of the total sample\]) and high intake of dietary fibres (defined as those above the upper tertile \[33.3% of the total sample\]) are independently associated with better treatment outcome, and their synergy (interaction between the factors meat and fibres) gives the best treatment outcome"

OTHER

Other (exploratory) exposure variables

"* Lifestyle factors independently or combined (red and processed meat, vegetable, dietary fibre, cereals, gluten, legumes, red wine, dairy products, physical activity, smoking, total protein/ fat, protein/ fat from red and processed meat, glucemic index)~* Pretreatment lifestyle-associated biomarkers~* Combinations of lifestyle factors and lifestyle-associated biomarkers~* Gene-environment interaction analyses~* Pretreatment levels of inflammatory molecules"

Trial Locations (3)

2730

Herlev Hospital, Herlev

5000

Odense University Hospital, Odense

6200

Hospital of Southern Jutland, Aabenraa

All Listed Sponsors
collaborator

Hospital of Southern Jutland

OTHER

collaborator

University Hospital Bispebjerg and Frederiksberg

OTHER

collaborator

University of Copenhagen

OTHER

collaborator

Odense University Hospital

OTHER

collaborator

University of Aarhus

OTHER

collaborator

Aalborg University Hospital

OTHER

collaborator

Herning Hospital

OTHER

collaborator

Esbjerg Hospital - University Hospital of Southern Denmark

OTHER

collaborator

Sygehus Lillebaelt

OTHER

collaborator

Aalborg University

OTHER

collaborator

University of Kiel

OTHER

collaborator

Colitis-Crohn Foreningen

OTHER

collaborator

Herlev Hospital

OTHER

collaborator

Regionshospitalet Silkeborg

OTHER

collaborator

Aarhus University Hospital

OTHER

collaborator

The Danish Psoriasis Association

UNKNOWN

lead

University of Southern Denmark

OTHER

NCT03173144 - Chronic Inflammatory Disease, Lifestyle and Treatment Response | Biotech Hunter | Biotech Hunter