Prevention of Neovascular Glaucoma by Intravitreal Injections of Anti-VEGF in Patients Treated with Proton Therapy for a Large Choroidal Melanoma

PHASE3CompletedINTERVENTIONAL
Enrollment

57

Participants

Timeline

Start Date

June 8, 2017

Primary Completion Date

January 31, 2025

Study Completion Date

January 31, 2025

Conditions
Ocular Melanoma
Interventions
DRUG

Aflibercept Injection

Intravitreal injection of aflibercept 40mg/mL will be done on patients. The injections will be performed on the last day of the proton therapy, then 1 and 2 months later for the induction phase. During the maintenance phase, injections will be performed every 3 months for a period of 21 months.

DRUG

False injection

A false injection will be done on patients on the last day of the proton therapy, then 1 and 2 months later for the induction phase. During the maintenance phase, falses injections will be performed every 3 months for a period of 21 months.

Trial Locations (1)

06003

CHU de Nice, Nice

All Listed Sponsors
lead

Centre Hospitalier Universitaire de Nice

OTHER

NCT03172299 - Prevention of Neovascular Glaucoma by Intravitreal Injections of Anti-VEGF in Patients Treated with Proton Therapy for a Large Choroidal Melanoma | Biotech Hunter | Biotech Hunter