Medication Misuse and Dependence Among Elderly

Active, not recruitingOBSERVATIONAL
Enrollment

500

Participants

Timeline

Start Date

May 3, 2017

Primary Completion Date

February 1, 2021

Study Completion Date

December 31, 2024

Conditions
Mild Cognitive ImpairmentElderlySubstance-Related Disorders
Interventions
DIAGNOSTIC_TEST

Substance misuse screening

Diagnostic and Statistical manual of mental disorders, version 4 (DSM-IV)/MINI-international Neuropsychiatric interview (MINI interview) for Diagnostics of dependence, additional questions for DSM-V classification, severity of dependence scale (SDS)

DIAGNOSTIC_TEST

EQ-5D

Health related Quality of life

DIAGNOSTIC_TEST

Impulsivity screening

Barratts impulsivity test v. 11, Behavioural inhibition/behavioural activation test

DIAGNOSTIC_TEST

Cognitive screening

Minimental state examination (MMSE), Hospital anxiety and depression scale (HADS), Trail-making test, clock drawing test

DIAGNOSTIC_TEST

Functional tests

Timed up and go (TUG), Single leg balancing test (SLB)

DIAGNOSTIC_TEST

Cognistat

Assessment of cognitive domains

DIAGNOSTIC_TEST

Neuropsychological profiling

Controlled Oral Word Association Test, Categorical fluency tests, Wechsler Adult Intelligence Scale, Color-Word Interference Test (CWIT) from the Delis-Kaplan Executive Function test

OTHER

Clinical interview

Interview for sociodemographics, utilisation of health care, economic varables, The De Jong Gierveld Loneliness Scale

OTHER

Medication use

Detailed screen of used medications, interactions, side effects in electronic patient registry

OTHER

Comorbidity

Charlson comorbidity index and Cumulated illness rating scale (CIRS) based on electronic patient registry

Trial Locations (1)

Unknown

Akershus University Hospital, Lørenskog

All Listed Sponsors
collaborator

King's College London

OTHER

collaborator

University of Oslo

OTHER

lead

University Hospital, Akershus

OTHER