22
Participants
Start Date
December 17, 2004
Primary Completion Date
June 2, 2009
Study Completion Date
December 2, 2009
Docetaxel
Docetaxel (28) is a semi-synthetic taxane which blocks mitosis by preventing microtubule depolymerization. It mediates its actions by binding to a different set of microtubule-associated proteins than paclitaxel. It is administered every 3 weeks as a 30 minute infusion at doses between 60 to 75 mg/m\^2.
Oxaliplatin
Alkylating antineoplastic agent. It is administered on day 1 of each cycle at a dose of 110 mg/m\^2
University of Pittsburgh Cancer Institute, Pittsburgh
Collaborators (1)
Sanofi-Synthelabo
INDUSTRY
Leonard Appleman
OTHER