50
Participants
Start Date
February 15, 2017
Primary Completion Date
March 1, 2019
Study Completion Date
March 1, 2019
Cardiac catheterisation
Pre-operative left heart catheterisation +/- right heart catheterisation
Cardiopulmonary exercise testing
Pre and post-operative cardiopulmonary exercise testing
Pulmonary function tests
Pre and post-operative pulmonary function tests
Cardiac MRI
Pre and post-operative cardiac MRI
Quality of life survey
Pre and post-operative quality of life survey (SF36)
Mitral valve operation
Clinically indicated mitral valve repair/replacement +/- coronary artery surgery +/- tricuspid valve surgery +/- atrial fibrillation surgery
Myocardial biopsies
Right and left epicardial ventricular biopsies taken at time of clinically indicated surgery
Hammersmith Hospital, London
Imperial College London
OTHER