Start or STop Anticoagulants Randomised Trial (SoSTART)

PHASE3CompletedINTERVENTIONAL
Enrollment

203

Participants

Timeline

Start Date

March 28, 2018

Primary Completion Date

March 26, 2021

Study Completion Date

March 26, 2021

Conditions
Intracranial HemorrhagesIntracranial Hemorrhage, HypertensiveSubarachnoid HemorrhageSubdural HematomaIntraventricular HemorrhageAtrial FibrillationAtrial FlutterSmall Vessel Cerebrovascular DiseaseMicrohaemorrhage
Interventions
DRUG

Apixaban

The participant will be allocated to start this oral anticoagulant drug, if the participant's doctor indicated it before randomisation.

DRUG

Rivaroxaban

The participant will be allocated to start this oral anticoagulant drug, if the participant's doctor indicated it before randomisation.

DRUG

Edoxaban

The participant will be allocated to start this oral anticoagulant drug, if the participant's doctor indicated it before randomisation.

DRUG

Dabigatran

The participant will be allocated to start this oral anticoagulant drug, if the participant's doctor indicated it before randomisation.

DRUG

Acenocoumarol

The participant will be allocated to start this oral anticoagulant drug, if the participant's doctor indicated it before randomisation.

DRUG

Phenindione

The participant will be allocated to start this oral anticoagulant drug, if the participant's doctor indicated it before randomisation.

DRUG

Warfarin

The participant will be allocated to start this oral anticoagulant drug, if the participant's doctor indicated it before randomisation.

Trial Locations (67)

EH16 4SB

Edinburgh Royal Infirmary, Edinburgh

AB25 2ZN

Aberdeen Royal Infirmary, Aberdeen

NP7 7EG

Nevill Hall Hospital, Abergavenny

ML6 0JS

Monklands Hospital, Airdrie

EN5 3DJ

Barnet Hospital, Barnet

BA1 3NG

Royal United Hospital, Bath

B9 5SS

Heartlands Hospital, Birmingham

BH7 7DW

The Royal Bournemouth Hospital, Bournemouth

BD9 6RJ

Bradford Royal Infirmary, Bradford

BS2 8HW

University Hospital Bristol, Bristol

CB2 0QQ

Addenbrookes Hospital, Cambridge

CF14 4XW

University Hospital of Wales/ /University Hospital Llandough, Cardiff

CO4 5JL

Colchester General Hospital, Colchester

DE22 3NE

Derby Royal Hospital, Derby

DH1 5TW

University Hospital North Durham, Durham

BT74 6DN

South West Acute Hospital, Enniskillen

EX2 5DW

Royal Devon & Exeter Hospital, Exeter

GU16 7UJ

Frimley Park Hospital, Frimley

NE9 6SX

Queen Elizabeth Hospital, Gateshead

ME7 5NY

Medway Maritime Hospital, Gillingham

G4 0SF

Glasgow Royal Infirmary, Glasgow

G51 4TF

Queen Elizabeth University Hospital, Glasgow

GL1 3NN

Gloucestershire Royal Hospital, Gloucester

HX3 0PW

Calderdale Royal Hospital, Halifax

HA1 3UJ

Northwick Park, Harrow

CF82 7EP

Ystrad Mynach Hospital, Hengoed

KY2 5AH

Victoria Hospital Kirkcaldy, Kirkcaldy

LA1 4NU

Royal Lancaster Infirmary, Lancaster

LS13EX

Leeds General Infirmary, Leeds

L78XP

Royal Liverpool and Broadgreen University Hospital, Liverpool

L9 7 AL

University Hospital Aintree, Liverpool

E1 1BB

The Royal London Hospital, London

E9 6SR

Homerton University Hospital, London

N18 1QX

North Middlesex University Hospital, London

NW1 2BU

University College London Hospital, London

SE1 7EH

St Thomas Hospital, London

SW17 OQT

St.George's Hospital, London

BT47 6SB

Altnagelvin Hospital, Londonderry

LU4 0DZ

Luton & Dunstable University Hospital, Luton

NG17 4JL

King's Mill Hospital, Mansfield

CH49 5EP

Arrowe Park Hospital, Metropolitan Borough of Wirral

TS4 3BW

James Cook University Hospital, Middlesbrough

NE1 4LP

Royal Victoria Infirmary, Newcastle upon Tyne

NG5 1PB

Nottingham City Hospital, Nottingham

OX3 9DU

John Radcliffe Hospital, Oxford

PE3 9GZ

Peterborough City Hospital, Peterborough

BH15 2JB

Poole Hospital, Poole

PR2 9HT

Royal Preston Hospital, Preston

RG1 5AN

Royal Berkshire Hospital, Reading

RM7 0AG

Queen' Hospital Romford, Romford

M6 8HD

Salford Royal NHS Foundation Trust, Salford

S10 2JF

Royal Hallamshire Hospital, Sheffield

SO16 6YD

Southampton General Hospital, Southampton

TS19 8PE

University Hospital of North Tees, Stockton-on-Tees

ST4 6QG

Royal Stoke University Hospital, Stoke-on-Trent

SR4 7TP

Sunderland Royal Hospital, Sunderland

SA6 6NL

Morriston Hospital, Swansea

TF1 6TF

The Princess Royal Hospital, Telford

TQ2 7AA

Torbay District General Hospital, Torquay

TR1 3LJ

Royal Cornwall Hospital, Truro

UB8 3NN

Hillingdon Hospital, Uxbridge

WF1 4DG

Pinderfields Hospital, Wakefield

SS0 0RY

Southend University Hospital NHS Foundation Trust, Westcliff-on-Sea

SO22 5DG

Royal Hampshire County Hospital, Winchester

WV10 0QP

New Cross Hospital, Wolverhampton

BA21 4AT

Yeovil District Hospital, Yeovil

YO31 8HE

York Hospital, York

All Listed Sponsors
collaborator

NHS Lothian

OTHER_GOV

lead

University of Edinburgh

OTHER

NCT03153150 - Start or STop Anticoagulants Randomised Trial (SoSTART) | Biotech Hunter | Biotech Hunter