Progesterone and Aminophylline for the Prevention of Preterm Labour

Progesterone 400mg to be administered once daily for 34 weeks in the patients randomised to receive progesterone alone

Patients randomised to the combination arm to be administered aminophylline 225 mg to be taken once at night for 1 week and then if tolerated increased to 225 mg twice daily Progesterone 400mg to be administered once daily for 34 weeks.