Assessment of Duodenal Epithelial Integrity in Celiac Disease With Mucosal Impedance

CompletedOBSERVATIONAL
Enrollment

33

Participants

Timeline

Start Date

December 31, 2016

Primary Completion Date

November 7, 2018

Study Completion Date

November 14, 2018

Conditions
Celiac Disease
Interventions
DIAGNOSTIC_TEST

Mucosal Impedance Catheter

During routine endoscopy, consented study participants will have a mucosal impedance catheter sensor positioned along the mucosal wall to measure resistance across the mucosa. The study procedure will add approximately 1-2 minutes of anesthesia time for each participant.

DIAGNOSTIC_TEST

Blood sample

At time of endoscopy, subjects with initial positive CeD serology will have a blood sample taken for any missing CeD serologies and intestinal fatty acid-binding protein (IFABP). This will be done at time of IV initiation as to avoid any additional venipuncture.

Trial Locations (1)

37232

Vanderbilt University Medical Center Endoscopy Laboratory, Nashville

All Listed Sponsors
lead

Vanderbilt University Medical Center

OTHER

NCT03152279 - Assessment of Duodenal Epithelial Integrity in Celiac Disease With Mucosal Impedance | Biotech Hunter | Biotech Hunter