Enteral Nutrition After Pancreaticoduodenectomy

NACompletedINTERVENTIONAL
Enrollment

120

Participants

Timeline

Start Date

September 30, 2016

Primary Completion Date

December 31, 2017

Study Completion Date

February 28, 2018

Conditions
Cancer of PancreasCancer of DuodenumAmpulla of Vater CancerCholangiocarcinoma
Interventions
OTHER

Early enteral nutrition

"Naso-jejunal tube will be placed intraoperatively. The distal end of the feeding tube would be placed at 30 cm distal to Treitz ligament. Standard enteral diet, administered through a nasojejunal tube, is started on the 1st postoperative day and increased daily by 20-40 ml up to the estimated level.~After PD, enteral nutrition liquid regimen will be used step by step from postoperative day 1 to postoperative day 7.Patients are targeted to receive calories for 25 kcal/kg/day. Meanwhile, oral food intake was not restricted."

OTHER

Saline

"Naso-jejunal tube will be placed intraoperatively. The distal end of the feeding tube would be placed at 30 cm distal to Treitz ligament.~After PPPD,Only Normal Saline were given through nasojejunal tube. Entral nutrition was not administrated. Patients intake food orally at will."

DEVICE

nasojejunal tube insertion

OTHER

Oral intake

Patients was encouraged to drink water on postoperative day 1, to eat liquid diet on postoperative day 2, to eat semi-solid on postoperative day 3, to eat solid food on postoperative day 4.

Trial Locations (1)

210029

The first affiliated hospital of Nanjing Medical University, Nanjing

Sponsors
All Listed Sponsors
lead

Nanjing Medical University

OTHER