Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep

PHASE2CompletedINTERVENTIONAL
Enrollment

32

Participants

Timeline

Start Date

July 27, 2016

Primary Completion Date

June 7, 2020

Study Completion Date

June 7, 2020

Conditions
Sleep Apnea, Obstructive
Interventions
DRUG

Oxytocin Intranasal Spray

In human volunteers intranasal administration of oxytocin significantly increases parasympathetic and decreases sympathetic cardiac control. In addition to the classic effects of oxytocin on uterine contraction and milk ejection, recent work indicates oxytocin is present in both males and females and has an important role in both behavior and cardiovascular homeostasis, particularly during anxiety and stress.

DRUG

Placebo Intranasal Spray

The placebo has been compounded to be an inactive, blinded comparative to the oxytocin nasal spray.

Trial Locations (1)

20037

The GW Medical Faculty Associates, Washington D.C.

All Listed Sponsors
lead

George Washington University

OTHER

NCT03148899 - Impact of Oxytocin on Obstructive Sleep Apnea Induced Changes in Sleep | Biotech Hunter | Biotech Hunter